Understanding the Relation Between Exocrine Pancreas (EPI) and Cystic Fibrosis

By: Researcher Taymur

Cystic fibrosis is a genetic disorder that causes thick, oily, rather than thin or runny body fluids. The lungs and digestive system are badly affected.

Individuals with cystic fibrosis have difficulty breathing because mucus blocks their lungs and makes them susceptible to infection. Thick mucus also blocks the pancreas and prevents digestive enzymes from being released. Roughly 90 per cent of cystic fibrosis patients also experience pancreatic insufficiency exocrine (EPI).

Continue to read about how these two conditions are related.

Understanding Cystic Fibrosis Causes

The CFTR gene deficiency is due to cystic fibrosis. Cells make sticky, dense liquids by a mutation in this gene. A young age is diagnosed with most people with cystic fibrosis.

Understanding Cystic Fibrosis Risk Factors

The genetic condition is cystic fibrosis. You have an increased risk of disease development if your parents have the disease or if they bear the defective gene. Two genes, one from each parent, must be inherited by a person with cystic fibrosis. You won’t get cystic fibrosis, but you’re a vector of the disease if you just have one copy of the gene. There is a 25 percent chance that your baby will develop cyst fibrosis if two gene carriers have a child. There is a 50% risk that your baby bears the gene but has no cystic fibrosis.

Also, more prominent in Northern European descent is cystic fibrosis.

Understanding Link EPI and Cystic Fibrosis

EPI is a major cystic fibrosis complication. After chronic pancreatitis, cystic fibrosis is the second most prevalent cause of EPI. That happens because your thick pancreas mucus prevents the entry of pancreas enzymes.

The absence of pancreatic enzymes means that much of the food in your digestive tract is untamed. In people with EPI, fats and proteins are especially difficult to digest.

This partial digestion and food absorption can result in:

1^st is abdominal pain
2^nd is bloating
3^rd is constipation
4^th is diarrhea
5^th is fatty and loose stools
6^th is weight loss
7^th is malnutrition

Cystic fibrosis can also make it difficult to maintain a healthy weight even if you eat a normal amount of food.

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Understanding EPI Available Treatments

You can control your EPI through a healthy lifestyle and a balanced diet. It includes limiting the intake of alcohol, avoiding smoking and eating a nutritious diet full of vegetables and whole grains. Many individuals with CF will consume a standard diet with 35 to 45% of calories of fat.

You should also take enzyme replacements to boost your digestion with all your foods and snacks. Increased use can help make your body unable to absorb vitamins from EPI.

If you cannot maintain good weight, your doctor can recommend you use an EPI feeding tube at night.

Even if you do not have a lower function at present because it can decline in future, your doctor needs to check your pancreatic function. This will improve the treatment of your condition and increasing the risk of further harm to your pancreas.

Understanding Giving’s

There were historically very short life expectancies for people with cystic fibrosis. Today, 80% of the cystic fibrosis population is male. This is due to great progress in diagnosis and control of the symptoms. There is therefore a great deal of optimism, even though there is still no cure for cystic fibrosis.